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Home Health

Biological age tests: Should you get one?

ohog5 by ohog5
August 30, 2025
in Health
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Biological age tests: Should you get one?
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Should you’ve heard of billionaire Bryan Johnson, you’ve possible encountered the phrase “bio age testing.”

Johnson, the topic of the Netflix documentary Don’t Die, says he’s on a quest to realize the bottom attainable “organic age” (often known as bio age).

He reportedly spends hundreds of thousands annually on anti-aging remedies—dozens of day by day dietary supplements, weekly acid peels for his pores and skin, injections to spice up collagen manufacturing, hyperbaric oxygen remedy, and plasma infusions extracted from his 17-year-old son’s physique.

To find out what’s working, Johnson has undergone quite a few exams to evaluate his bio age. Johnson says these exams present his age is now 5.1 years youthful than when he launched into his anti-aging quest.

Apparently, he’s growing older in reverse.

Granted, not everybody’s shopping for it. A New York Instances exposé, for instance, claims Johnson’s organic age, in actuality, has elevated by 10 years.1

Nonetheless, Johnson’s “don’t die” campaign is gaining traction.

Bio age exams are a frequent matter on widespread podcasts by Peter Attia, Joe Rogan, and Andrew Huberman. Google “bio age testing” and also you’ll see dozens of adverts for mail-order blood or urine testing kits that declare to disclose your organic age, tempo of growing older, and extra. With costs tumbling into affordability, it’s pure to surprise…

Must you or your consumer join bio age testing?

If that’s the case, which take a look at is greatest? Simply as importantly, what do you have to do with the knowledge?

On this story, you’ll be taught:

What’s your bio age?

Your organic age (bio age) refers to how your cells operate. It’s not essentially the identical as your chronological age, which refers back to the variety of candles in your birthday cake.

For instance, let’s say Chang, a 50-year-old man, works at a desk, spends his free time in entrance of the TV, lives in probably the most polluted metropolis on the planet, eats a sweet bar for lunch, and smokes. Alternatively, Jabari, a unique 50-year-old man, hits the health club a number of instances every week, lives within the mountains, doesn’t smoke, relishes his 5 servings of veggies a day, meditates, and spends most evenings in his backyard.

Genetics apart, you’d be sensible to wager that Jabari’s bio age is youthful than Chang’s.

How do these exams measure bio age?

Bio age testing kits measure a number of organic markers of growing older, often known as biomarkers.

For instance, some exams give attention to the dimensions of your telomeres, the protecting caps on the ends of chromosomes. Others measure DNA methylation, a physiological course of that chemically alters DNA.

As soon as an organization isolates and measures these markers out of your blood or urine, it plugs the bio knowledge right into a system that calculates your bio age.

Nonetheless, should you see a physician with any regularity, you’re possible already monitoring some biomarkers of growing older. For instance, biomarkers comparable to blood stress, levels of cholesterol, and blood glucose may also help predict your threat of future heart problems, a number one explanation for untimely dying.

What’s the purpose of biomarker testing?

Biomarker testing may also help you monitor your wellness proactively fairly than ready for illness signs to seem.

For some, it additionally serves as a motivator. Should you be taught you may have the bones of somebody 20 years older, this will provide the nudge it’s essential to begin power coaching persistently.

As well as, biomarkers present goal knowledge, permitting you to trace and consider numerous health-related actions quantitatively. By monitoring your blood stress, you may be taught that constant train helps, however your late-afternoon vitality drink does the other.

5 FREE biomarker exams

You don’t need to be a billionaire (or perhaps a millionaire) to trace biomarkers of growing older.

On this part, we’ll cowl a number of massively underappreciated, scientifically validated exams you need to use to achieve perception into your bio age—for FREE.

Earlier than scientists developed high-tech blood-based bio age exams, researchers used these free exams to calculate the tempo of growing older within the folks they studied.

FREE biomarker take a look at #1: Get off the ground

People who find themselves fitter and stronger are inclined to stay longer.2

That’s as a result of muscle tissues do extra than simply transfer us round. Additionally they secrete anti-inflammatory substances, assist to manage blood sugar, sluggish mobile growing older, defend the liner of the arteries, and extra. All this helps scale back the chance of age-related ailments, comparable to sort 2 diabetes, hypertension, and coronary heart illness, a phenomenon we discover in our article, The New Science of Muscle.

Associated to power, your means to steadiness can be key. Should you’re middle-aged or older and may’t stand on one foot for at the least 10 seconds, your threat of dying within the subsequent seven years is double that of somebody who can stand for longer, in accordance with a research of 1,700 folks.3

The Sitting-Rising Check (SRT) is one technique to assess each power and steadiness on the identical time.

Individuals with low scores on this take a look at have the next threat of dying from heart problems, in accordance with a 12-year research of 4,200 adults between the ages of 46 and 75.4

▶ How you can measure it

Decrease your self to the ground together with your legs in a crisscross place. Then, together with your legs in the identical place, stand again up. As you stand, discover should you should use part of your physique—hand, shin, knee—as leverage.

To attain your self, begin with 10 factors. Then, for every physique half you used to face, deduct a degree. Subtract a half level should you turned unsteady or misplaced your steadiness.

Understand that this (and different exams) function a proxy in your health. A low rating signifies that your steadiness and coordination, muscle power and energy, and mobility could all require some consideration.

FREE biomarker take a look at #2: Squeeze a ball

Just like the SRT take a look at, your grip power offers perception into your general health. If the muscle tissues in your arms are weak, the muscle tissues all through your physique usually tend to be weak, too.

Poor grip power also can predict future muscle weak point. In a single research, folks with a weak grip have been extra more likely to stroll slowly and be unable to rise from a chair, full rigorous home tasks, or climb a flight of steps 25 years later.5

Low grip power has additionally been related to:6

  • Low bone mineral density
  • Elevated threat of falls
  • Poor dietary standing
  • Despair
  • Poor sleep, cognitive operate, and/or high quality of life
  • Elevated threat of coronary heart illness, most cancers, and untimely mortality

In line with one research, grip power was a greater indicator of longevity (or lack thereof) than blood stress.7

▶ How you can measure it

Seize a typical tennis ball, and squeeze as laborious as you’ll be able to, for so long as you’ll be able to.

Should you can handle 15 to 30 seconds earlier than your grip fatigues, you’re doing superb. Ninety seconds places you properly above common—something over 90 ranks you solidly within the upper-third percentile.

Should you’re beneath 15, needless to say this take a look at can be only one indicator of your general power. (And squeezing balls to enhance grip power with out coaching the remainder of your physique is unlikely to make important enhancements in your general well being and health.)

A hand-held dynamometer—obtainable to be used at most occupational therapists’ and a few gyms—also can take a look at grip power. (Should you’re prepared to shell out some money, you should buy your individual for someplace between $100 and $500.)

FREE biomarker take a look at #3: Stand on one foot

A capability to steadiness on one foot for an prolonged interval may also help scale back your threat of falls, one of many main causes of injury-related dying amongst older adults.

As well as, many alternative bodily programs—the eyes, interior ear, skeletal muscle tissues, and mind—should work collectively that can assist you keep upright.

Situations like diabetes, coronary heart illness, and most cancers can all have an effect on steadiness. Because of this, an incapability to face on one foot can function a warning signal for eroding well being and health.8

▶ How you can measure it

Stand close to a wall or chair for security. Hold your eyes open and arms in your hips. Then, carry your dominant leg and begin timing your self. As soon as you set your foot down, cease the clock. Repeat the take a look at together with your non-dominant leg.

After you have your instances, examine them to the next averages, from a research out of Duke College, to see how you probably did in comparison with your age-matched friends.9

Age Seconds on one leg (males) Seconds on one leg (females)
30-39 59 56
40-49 56 55
50-59 42 48
60-69 40 38
70-79 27 25
80+ 13 11

FREE biomarker take a look at #4: How you are feeling

Generally you understand why you’re drained, such because the morning after binge-watching the previous few episodes of a thriller. When you compensate for your sleep, the weariness lifts.

That’s not the identical factor as fatigue, which describes persistent exhaustion that worsens over time and interferes with life. Along with feeling bodily drained, somebody who’s fatigued feels mentally uninteresting and emotionally exhausted.

Consider fatigue as an early signal that one thing’s off, particularly should you don’t know the trigger.

Let’s say you’ve already dominated out the standard suspects like an excessive amount of caffeine, dehydration, an excessive amount of alcohol, treatment negative effects, power stress, or an excessive amount of or too little train. What’s left is probably going a sleep problem or a creating well being downside comparable to anemia, weight problems, despair, most cancers, or diabetes, to call just a few.

Should you’re 60 or older, fatiguability—or how worn out you are feeling after an exercise—also can predict longevity.

In line with analysis out of the College of Pittsburgh Medical Heart, the upper somebody scores in fatiguability, the upper their threat of dying sooner or later.10 Different analysis has linked excessive fatiguability with declines in gait pace, strolling means, and different exams of health.11

▶ How you can measure it

To measure fatigability, use a device referred to as the Pittsburgh Fatigability Scale. Utilizing a 0 (no fatigue) to five (excessive fatigue) scale, fee how fatigued you assume you’d really feel after finishing the next actions:

Exercise Period Rating (0 to five)
Leisurely strolling half-hour
Brisk or quick strolling 1 hour
Mild family exercise 1 hour
Heavy gardening or yard work 1 hour
Watching tv 2 hours
Sitting quietly 1 hour
Reasonable-to-high depth power coaching half-hour
Collaborating in a social exercise 1 hour
Internet hosting a social occasion for 60 minutes 1 hour
Excessive depth exercise half-hour
Add all scores:

Should you rating lower than 15, you’re doing properly. Scores between 15 and 24 are a warning signal. Something 25 and above is considered extreme, and price mentioning to your healthcare skilled.12

FREE biomarker take a look at #5: Physique composition

Regardless of widespread perception, each too little and an excessive amount of physique fats can affect well being for the more severe, as we discover in our infographic, Is body fat good or bad for you?

An excessive amount of fats raises the chance for: Too little muscle raises threat for:
Coronary heart illness Coronary heart illness
Hypertension Hypertension
Most cancers Most cancers
Fatty liver illness Stroke
Insulin resistance Insulin resistance
Kind 2 diabetes Sooner mobile growing older
Irritation Irritation
Joint misery Despair and nervousness
Sleep apnea Falls and lack of steadiness

Your muscle mass additionally performs a job, which is why somebody’s physique composition issues greater than their weight.

The gold commonplace strategies that estimate physique composition—underwater weighing, air displacement (Bod Pod), and dual-energy X-ray absorptiometry (DEXA)—actually aren’t free.

Nonetheless, a latest research decided {that a} good old school (and low-cost) tape measure can present a comparably correct estimate of physique composition.13

▶ How you can measure it

To make use of a tape measure to maintain monitor of your physique fats share, measure:

  • The widest a part of your neck
  • The narrowest a part of your waist (For some folks, this will likely be on the navel. For others, it may be barely above the navel)
  • The widest a part of your hips

Make sure the tape is cosy however not so tight that it cuts into the pores and skin. After you have your measurements, plug these numbers—alongside together with your age, intercourse, top, and weight—into our FREE Body Fat Calculator, which is able to take it from there.

Physician-approved biomarker exams

Relying on the place you reside on the planet, the next exams might not be free. Nonetheless, as a part of routine preventative care, your insurance coverage may cowl them.

Physician-approved take a look at #1: Blood panel

In case your major care physician recommends yearly blood work, it’s for good purpose.

By conserving tabs on a number of blood markers, you’ll be able to see in case your well being is trending towards sort 2 diabetes or coronary heart illness, each main causes of untimely mortality.

Many blood markers will also be influenced comparatively rapidly (inside 6 to 12 weeks) by life-style modifications, complement protocols, or medicines. This makes them sensible instruments for monitoring whether or not numerous life-style or medical modifications are working.

▶ How you can measure it

Should you’re not already doing so, take into account having the next blood markers examined yearly. Then, discuss to your well being care skilled about what your numbers imply. They could use the next numbers, alongside together with your blood stress, to calculate a heart problems threat rating.

Blood marker Optimum vary
Complete ldl cholesterol < 200 mg/dL*
LDL < 100 mg/dL for these with out coronary heart illness
< 70 mg/dL for these with a historical past of coronary heart assault or stroke
HDL > 60 mg/dL
Triglycerides < 150 mg/dL
Alipoprotein B (Apo B) < 133 mg/dL (males)
< 117 mg/dL (females)
Lipoprotein (a) < 30 mg/dL
C-reactive protein < 2.0 mg/L**
Fasting glucose < 100 mg/dL
Hemoglobin A1C < 5.7%

*Milligrams per deciliter of blood
**Milligrams per liter

Physician-approved take a look at #2: Bone density

When researchers research wholesome super-agers aged 90 and older, sturdy bones are one in all their defining options.14

Which may be as a result of, like muscle tissues, bones are stay organs that secrete substances which may be useful to general well being and longevity.15

For instance, bones secrete osteocalcin, a hormone that performs a job in bone reworking. When osteocalcin circulates within the physique, it’s thought to play a job in the whole lot from serving to muscle tissues to supply ATP to regulating mind neurotransmitters.

Due to these different roles, it’s thought that, as bones put on away, osteocalcin ranges drop, contributing to many age-related well being issues, together with diabetes, low muscle mass, and cognitive points.16 17 (Not less than, that’s the speculation. Most of this analysis has been executed on mice.)

Osteocalcin apart, lack of bone density can, after all, result in fractures, which might enhance your threat of dying for as much as 10 years after a break.18

It’s particularly necessary to maintain tabs on bone well being should you’re in any of those high-risk classes:

  • You’re feminine and went by menopause earlier than age 45.
  • You’ve been sedentary most of your grownup life.
  • You are taking medicines comparable to diuretics or stomach-acid blockers, that are linked with an elevated threat of osteoporosis.
  • You have got a historical past of nicotine use or extreme alcohol consumption.
  • You have got a medical situation, comparable to diabetes or thyroid illness, that raises your threat.
  • You have got a household historical past of osteoporosis.

▶ How you can measure it

Twin-energy X-ray absorptiometry (DEXA) scans are a kind of X-ray that measures the quantity of bone mineral content material packed right into a sq. centimeter of bone.

Insurance coverage typically gained’t cowl these scans for folks youthful than 65 except there’s a documented threat of creating osteoporosis. Out of pocket, the common value is about $300.

Once you obtain your DEXA outcomes, you’ll see a T-score that represents how your bone density compares to the common bone density of a younger grownup with peak bone mass. A T-score of +1.0 to -1.0 means you may have regular bone mineral density for somebody your age. Something beneath -1.0 means you may need osteopenia (low bone mineral density) or osteoporosis (porous bones which are vulnerable to fracture).

Business bio age exams

When you’ve got some cash to burn, you’ll be able to be taught an terrible lot about your physique.

Right here, you’ll discover a fast run-down on among the extra high-tech exams you may get and what they will inform you.

Nonetheless, earlier than we get into the small print, we wish to level out just a few caveats:

▶ Organic age can fluctuate over time, and by organ. Somebody could undergo a interval of accelerated growing older—saying, throughout a interval of intense stress—then their fee of growing older could sluggish as they focus extra on restoration. Moreover, organs can age at completely different charges. For instance, somebody with coronary heart illness could have a comparatively older coronary heart than their kidneys. (Not all exams measure particular person organ age, however it’s changing into extra widespread.)

▶ Business exams gained’t at all times precisely replicate the modifications you’re making. Till extra analysis helps the reliability of those exams, consider your behaviors over remoted take a look at outcomes. Should you’re consuming extra fruits and veggies, exercising extra persistently, managing stress, and in any other case slaying the wholesome life-style division, don’t sweat your outcomes. Deal with doing the issues we all know enhance well being.

▶ If an organization pairs your take a look at outcomes with a tough promote for a proprietary and costly complement protocol, be cautious. It’s higher to share and talk about your outcomes with a trusted well being skilled than take well being recommendation from a profit-seeking stranger over the web.

Business take a look at #1: DNA methylation

DNA methylation is a organic course of that chemically alters DNA. As a result of the speed of methylation accelerates with growing older, it may be used to estimate somebody’s organic age and life expectancy, finds analysis.19 20 21

The Horvath Clock and DunedinPACE each measure particular biomarkers that can be utilized to raised perceive somebody’s methylation fee. Scientists developed these exams to assist different scientists research how numerous life-style elements, environmental exposures, and medicines have an effect on growing older. They didn’t develop the exams as a means for the common individual to pinpoint their organic age. (Which hasn’t stopped corporations from promoting DNA methylation testing kits to the general public.) They value about $300.

Should you resolve to get one in all these exams, have in mind your outcomes gained’t offer you an entire image of your well being and longevity. Ageing usually happens at various charges all through the physique. Your liver may age quicker than your coronary heart or mind, for instance. So should you measure DNA methylation in your blood, that’s all you understand about. Put one other means, a DNA methylation take a look at isn’t an alternative choice to your annual wellness checkup or blood work.

Business take a look at #2: Telomere evaluation

Telomeres—the protecting caps on the ends of chromosomes—put on away with age. The size of a telomere can predict what number of instances a selected cell can divide earlier than dying.

Abnormally brief telomeres are related to a number of genetic ailments. Because of this, when physicians suspect somebody may need inherited a genetic illness, they’ll order a selected sort of telomere take a look at—the flow-FISH take a look at—to measure the telomere size in all of the cells in a blood pattern.22 23

It’s extra debatable whether or not telomere exams can predict growing older in wholesome folks.

Simply as importantly, the telomere take a look at marketed to the general public, often called the qPCR telomere take a look at, isn’t utilized in analysis or drugs. These $100 exams are superb should you’re merely curious—simply don’t base well being and health selections in your outcomes.

Business take a look at #3: VO2 Max

For years, solely elite athletes cared about VO2 max, which describes the utmost quantity of oxygen that your physique can use throughout train.

Extra lately, nevertheless, some specialists have instructed that VO2 max can function a measure for athletes and non-athletes alike to trace the speed at which their our bodies are growing older.

Individuals with excessive VO2 max have a tendency not solely to be extra bodily match but additionally much less more likely to develop coronary heart illness, diabetes, most cancers, or stroke.24 25 26 27

In an observational research that adopted the well being outcomes of 5,107 Danish males over 46 years, males with above-average V02 max throughout center age lived a mean of 5 years longer than males with below-average V02 max. Every unit enhance in VO2 max was related to a 45-day enhance in longevity. The researchers instructed VO2 max could extra precisely predict all-cause mortality than excessive ldl cholesterol, weight problems, hypertension, and insulin resistance.28

You may consider V02 max as a canary and your growing older physique as a coal mine.

As you age, your chest wall turns into extra inflexible, the muscle tissues that encompass the lungs weaker, and the oxygen-carrying blood vessels calcified and fewer elastic. The center additionally squeezes with much less drive, max coronary heart fee drops, muscle mass and power decline, the mitochondria in cells and muscle tissues lose their effectiveness, amongst different variations.

Along with elevating your threat for a lot of completely different ailments, these modifications also can have an effect on VO2 max, which tends to say no 10 p.c per decade beginning round age 30.29 30

Prior to now, the one technique to reliably measure VO2 max was in a health lab.

You’d put on a metabolic masks and a coronary heart monitor whilst you ran or cycled to exhaustion. The masks collected your expired carbon dioxide and monitored how a lot oxygen you sucked into your lungs. This lab-based testing remains to be probably the most correct technique to measure V02 max in addition to different key health metrics comparable to:

  • Max coronary heart fee, or the very best variety of instances your coronary heart can beat per minute throughout train
  • Ventilatory threshold 1, or the purpose throughout train when the physique switches from primarily utilizing fats for gas to utilizing a mixture of fats and glucose or glycogen (saved glucose) for gas.
  • Ventilatory threshold 2, or the purpose the place your physique strikes away from cardio metabolism (which makes use of oxygen) to anaerobic metabolism (which doesn’t use oxygen).
  • Tidal quantity is the quantity of air inhaled or exhaled throughout every breath

Relying on the place you reside, you may be capable to get your VO2 max examined for round $150.

Nonetheless, should you don’t have entry to a VO2 max clinic, three considerably much less correct choices exist.

▶ The 1-mile stroll take a look at

Put on a coronary heart fee monitor as you stroll one mile on a flat floor, comparable to a treadmill or operating monitor. As quickly as you full the mile, file your coronary heart fee and stroll time. Then, plug it into the next system to calculate your VO2 max:

132.853 — (0.0769 × Weight) — (0.3877 × Age) + (6.315 × Intercourse) — (3.2649 × Time) — (0.1565 × Coronary heart fee)

If that seems like an excessive amount of math, you can too use a free online tool.

▶ The smartwatch take a look at

Many smartwatches will estimate your VO2 Max for you based mostly on data the watch gathers out of your exercises, intercourse, and age. In comparison with in-office testing, sensible watches can over- or underestimate V02 max, particularly in people who find themselves very out of form or extraordinarily match.31

Due to this, you don’t essentially wish to use your sensible watch measurement to find out your present state of well being. Nonetheless, it can enable you to to see developments. For instance, does your VO2 estimate drop after just a few weeks of skipping your standard spin class? If that’s the case, that’s good data to have.

▶ The PR take a look at

Health efficiency correlates with longevity. Should you’re getting quicker at operating a sure distance or can go an extended distance than earlier than, you’re getting fitter and growing your probabilities of residing an extended, wholesome life.

One technique to take a look at this: the 12-minute run take a look at, often known as the Cooper take a look at. (It is a validated technique to estimate VO2 max—and reveals a couple of 90 p.c correlation with lab-based measurements.)

Right here’s the way it works:

Run as quick as you’ll be able to on a flat floor, comparable to a treadmill set at a 1 p.c incline or operating monitor, for 12 minutes. After 12 minutes, file your distance. Then, plug it into one of many following formulation to calculate your VO2 max.

Distance in Miles Distance in Kilometers
VO2 Max = (35.97 x distance in miles) – 11.29 (22.351 x distance in kilometers) – 11.288

In lieu of doing math, you can too use a free online calculator.

How you can change your organic age

Attempt to think about the knowledge you collect about your physique as simply that—data.

It’s not an ethical judgment of who you might be as an individual.

Simply as importantly, it’s not a everlasting state of affairs.

  • Should you’re weaker than different folks your age, you’ll be able to develop stronger.
  • In case your ldl cholesterol or blood glucose ranges are excessive, you’ll be able to take steps to decrease them.
  • In case your physique is growing older quicker than your birthdays, take into account exploring key life-style modifications that will assist flip the state of affairs round.

You have got choices. Nonetheless, most individuals make two massive errors on the subject of longevity-related life-style modifications.

Mistake #1: Ignoring evergreen, big-impact methods

It’s the straightforward, boring, “I’ve heard this one million instances earlier than” well being practices that, when executed persistently, add as much as an extended, wholesome life.

We’re speaking about issues like…

  • Consuming extra minimally processed meals and fewer ultra-processed meals
  • Consuming extra brightly coloured fruits and veggies
  • Transferring your physique repeatedly
  • Getting sufficient relaxation and sleep
  • Having fun with group, time in nature, and different actions that make life significant
  • Maintaining alcohol consumption reasonable
  • Not utilizing tobacco
  • Sporting sunscreen
  • Flossing

And that’s only a partial listing.

In line with 1000’s of research, individuals who apply these and different high-impact methods not solely stay longer, but additionally stay higher. They’re stronger, happier, and fewer more likely to spend their later years disabled or in ache.

(Should you’d wish to see the place you stand on the subject of massive impression well being and longevity methods, take a look at our FREE Longevity Assessment.)

Nonetheless, on the subject of well being, health, and longevity, many individuals pursue choices with minimal impression (at greatest). They attain for the most recent, fashionable complement fairly than taking steps to give up smoking, as only one instance.

Right here’s the factor: Huge rock methods require modifications in conduct. If day by day bodily exercise have been as simple as popping a tablet, walkers and cyclists would clog up the streets in your neighborhood.

(It’s exactly this purpose why so many individuals want the assist of a certified health coach who has undergone coaching within the science of conduct change.)

Mistake #2: Not turning knowledge into motion

The information gathered from biomarker growing older exams may give you a way of management.

Nonetheless…

Information, in isolation, doesn’t result in an extended life.

Gathering knowledge with out altering your conduct is like checking your reflection within the mirror, seeing spinach wedged between your incisors, and leaving it there.

You want to take away the spinach for the mirror examine to be worthwhile.

Biomarker testing is similar.

Should you don’t use your bio knowledge to tell conduct change, you’re losing your time and cash.

Take into account your biomarker knowledge as a baseline or place to begin.

Then, use it to evaluate whether or not numerous life-style modifications or medical interventions are transferring you nearer to your purpose of residing an extended, more healthy life.

References

Click on right here to view the knowledge sources referenced on this article.

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2. Strasser B, Volaklis Okay, Fuchs D, Burtscher M. Role of dietary protein and muscular fitness on longevity and aging. Ageing Dis. 2018 Feb 1;9(1):119–32.

3. Araujo CG, de Souza E Silva CG, Laukkanen JA, Fiatarone Singh M, Kunutsor SK, Myers J, et al. Successful 10-second one-legged stance performance predicts survival in middle-aged and older individuals. Br J Sports activities Med. 2022 Sep 1;56(17):975–80.

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7. Leong DP, Teo KK, Rangarajan S, Lopez-Jaramillo P, Avezum A Jr, Orlandini A, et al. Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study. Lancet. 2015 Jul 18;386(9990):266–73.

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9. Corridor KS, Cohen HJ, Pieper CF, Fillenbaum GG, Kraus WE, Huffman KM, et al. Physical performance across the adult life span: Correlates with age and physical activity. J Gerontol A Biol Sci Med Sci. 2017 Apr 1;72(4):572–8.

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11. Simonsick EM, Schrack JA, Santanasto AJ, Studenski SA, Ferrucci L, Glynn NW. Pittsburgh Fatigability Scale: One-page predictor of mobility decline in mobility-intact older adults. J Am Geriatr Soc. 2018 Nov 1;66(11):2092–6.

12. Vercelli S, Zampogna E, Negrini F, Pietraroia C, D’Antona G, Papa S, et al. Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale – Italian version (PFS-I) in a mixed-sample of older adults. BMC Geriatr. 2024 Dec 19;24(1):1016.

13. Combest TM, Khan J, Tufano JJ, Lane M, Watson NL, Altom KR, et al. Comparison of four body composition methods: Circumference measurements, eight-point bioelectrical impedance analysis up to 500 and 1000 kHz to dual-energy X-ray absorptiometry to measure body fat percentage. Mil Med [Internet]. 2024 Sep 18 [cited 2025 Jan 11]

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