A brand new examine means that psychological well-being could also be essential for wholesome ageing.
Research of Blue Zones, areas the place individuals generally stay to older ages, recommend {that a} strong sense of purpose is linked with longer life.
New analysis from UC Davis signifies that function might supply one other benefit as individuals grow old: a decrease threat of dementia.
The examine, printed in The American Journal of Geriatric Psychiatry, tracked greater than 13,000 adults aged 45 and above for as much as 15 years.
Individuals who reported the next sense of function have been about 28% much less more likely to develop cognitive impairment, together with delicate cognitive impairment and dementia.
The protecting impact of getting a function was seen throughout racial and ethnic teams. It additionally remained vital even after accounting for training, melancholy and the APOE4 gene, which is a identified threat issue for Alzheimer’s disease.
Purpose in life helps the brain stay resilient
“Our findings show that having a sense of purpose helps the brain stay resilient with age,” said Aliza Wingo, senior author and professor in the UC Davis Department of Psychiatry and Behavioral Sciences. “Even for people with a genetic risk for Alzheimer’s disease, sense of purpose was linked to a later onset and lower likelihood of developing dementia.”
Participants were not specifically asked about the activities that gave their life purpose. Previous studies on aging, though, have found a wide range of activities give older adults a sense of life purpose, sometimes referred to as “ikigai.” These include:
- Relationships: Caring for family, spending time with grandchildren, or supporting a spouse or friend.
- Work or volunteering: Continuing professional work, mentoring, or contributing to community causes.
- Spirituality or faith: Religious beliefs, spiritual practices or involvement in faith-based communities.
- Personal goals: Pursuing hobbies, learning new skills, or setting and achieving personal milestones.
- Helping others: Acts of kindness, philanthropy, caregivin,g or advocacy work.
Purpose delays onset of cognitive decline
Researchers also found that people with higher purpose tended to experience cognitive decline later than those with lower purpose. On average, the delay in onset was very modest — about 1.4 months over an eight-year period, after considering the effects of age, education, depressive symptoms, and genetic risk. However, it is meaningful when compared to current treatments.
“While medications like lecanemab and donanemab can modestly delay symptoms of cognitive impairment in Alzheimer’s disease, they come with risks and costs,” said Nicholas C. Howard, first author and public health researcher at UC Davis. “Purpose in life is free, safe, and accessible. It’s something people can build through relationships, goal,s and meaningful activities.”
Methods and limitations of study
Participants in the study were part of the Health and Retirement Study, a nationally representative survey funded by the National Institute on Aging. All had normal cognitive health at the beginning of the study.
Researchers used a seven-item survey from the Ryff Measures of Psychological Well-being. Participants had six possible responses (from “strongly agree” to “strongly disagree”) for statements such as: “I am an active person in carrying out the plans I set for myself” and “I have a sense of direction and purpose in my life.” Their answers were scored and averaged to obtain a well-being number between 1 and 6, with higher values indicating a strong sense of purpose in life.
Their cognitive health was tracked using a telephone-based test every two years.
The researchers noted the study has many strengths, including the size of the population studied. However, a key limitation is that although there was an association, the study did not prove higher levels of purpose caused the lowered rates of dementia.
Findings support role of psychological well-being
Still, the findings support the idea that psychological well-being plays a key role in healthy aging, said Thomas Wingo, a co-author of the study and a professor and neurologist at UC Davis Health. Wingo hopes future studies will explore whether purpose-building interventions can help prevent dementia.
“What’s exciting about this study is that people may be able to ‘think’ themselves into better health. Purpose in life is something we can nurture,” he said. “It’s never too early — or too late — to start thinking about what gives your life meaning.”
Reference: “Life Purpose Lowers Risk for Cognitive Impairment in a United States Population-Based Cohort” by Nicholas C. Howard, Ekaterina S. Gerasimov, Thomas S. Wingo and Aliza P. Wingo, 5 June 2025, The American Journal of Geriatric Psychiatry.
DOI: 10.1016/j.jagp.2025.05.009
Funding: NIH/National Institutes of Health, Department of Veterans’ Affairs
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