In a brand new podcast episode, a neuroscientist discusses a “grand plan” to higher deal with melancholy, Alzheimer’s, and Parkinson’s after a long time of struggles.
For many years, neuroscience has promised breakthroughs in treating situations like depression, schizophrenia, and Alzheimer’s. But regardless of highly effective applied sciences and billions invested, progress has been frustratingly sluggish. Why?
On this episode of Large Brains, Nicole Rust, a neuroscientist on the College of Pennsylvania and writer of Elusive Cures (2025, Princeton Press).
Rust argues that the standard “domino” view of the mind—the place one damaged piece can merely be mounted—has held us again. As a substitute, she says we have to embrace the mind’s true nature: a posh, dynamic system extra just like the climate than a machine.
Rust explains why remedies so usually fail, what makes temper such a scientific thriller, and whether or not a brand new period of mind analysis—powered by fashions, suggestions loops, and recent methods of considering—can lastly ship the cures which have lengthy eluded us:
Read the transcript of this episode.
Supply: University of Chicago











